What is CAR-T Cell Immunotherapy?

CAR-T is a personalized immunotherapy made from a patient’s white blood cells. The blood cells are removed from the patient and then modified with chimeric antigen receptors (CARs) so they can attack specific proteins. The cells are then infused back into the patient in the hospital.

CAR-T therapy has been approved for treating certain types of blood cancers. Clinical trials are now underway to see if it will be effective in treating metastatic breast cancer. You can find the breast cancer CAR-T trials now enrolling patients below.

CAR-T Therapy: An Overview

Current CAR-T Trials:

More immunotherapy articles on breastcancertrialtalk.org/

Managing Lymphedema

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Lymphedema–swelling of the arm, hand, breast, or torso–is a side effect that can develop after breast surgery or radiation that can affect the quality of life of individuals living with metastatic breast cancer. Below are websites and organizations that provide lymphedema-related information and support.

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Biosimilar Drugs & Breast Cancer

A biosimilar drug is a treatment that is highly similar to and that has the same efficacy as an approved biologic medicine. To date, one biologic has been approved for breast cancer care. More are expected.

Below you will find a podcast, video and article that can help you understand what biosimilar drugs are, how they are prescribed, and why they have the potential to decrease the cost of cancer treatments.

CRISPR & Cancer

CRISPR is short for Clustered Regularly Interspaced Short Palindromic Repeats. And if you follow science news, you’ve been hearing it a lot lately. What do you need to know about CRISPR and cancer?

First, we’ve got a Wired video that explains CRISPR in 5 different ways, so you, too, will know what everyone’s talking about. Next up is an article on how CRISPR might be used to treat cancer. And after that, there’s two articles on the recent finding that CRISPR results in more DNA damage than initially thought–and may cause cancer.

Chemo, Second Opinions & Disability Insurance

There’s many ways to hear from the experts. In this OncLive video, you can hear Joyce O’Shaughnessy, MD, talk about chemotherapy options for patients with metastatic breast cancer.

On Living Beyond Breast Cancer, you can read this Ask the Expert Q&A wtih William Gradishar, MD on how to get a second opinion.

And in this webinar from SHARE, you can learn about options for disability insurance from Caroline L. Bersak, from the Family Center’s Legal Wellness Institute.