Decoding Clinical Trial Terms: Dose Escalation and Dose Expansion
If you are considering enrolling in a clinical trial and/or are reading clinical trial results, you may see unfamiliar terms about different types of clinical trials. This month, we continue our series about clinical trial terms by discussing dose escalation and dose expansion. These are terms you may see if you are learning about a phase I trial.
- US Food and Drug Administration: The FDA defines dose escalation and many other clinical trial-related terms
- University of Massachusetts Medical School (video): Dr. Terence Flotte explains why dose escalation is part of phase I clinical trials
- Synapse: Dose expansion comes after dose escalation and is done to further understand the effects of a drug on a larger number of participants